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Postpartum Psychosis: A Review of Pharmacological Therapy Options

Tarih: 22/06/2023 | Yazar: admin

Postpartum Psikoz: Farmakolojik Tedavi Seçeneklerinin Derlemesi

Yazar: Barış ÖRS1

Corresponding author
1Barış ÖRS, Ankara Üniversitesi Tıp Fakültesi Dönem 6, Ankara, Türkiye
E-mail: orsbaris1@gmail.com

ABSTRACT

Postpartum psychosis is a severe postpartum mental health emergency characterized by mood swings, abnormal thinking or behavior, and confusion. Factors such as hormonal and psychological changes in the mother during pregnancy and the postpartum period, stress and a psychiatric disorder play an essential role in the development of postpartum psychosis, together with a genetic predisposition. Although this condition is most common in patients who have been or will be diagnosed with bipolar disorder, it may also occur less frequently in women with psychosis, schizophrenia, or major depression with schizoaffective disorder. In some patients, this situation may remain isolated in the postpartum period and not progress to any mood-destroying or psychotic disorders in the future. In a group of patients, this psychosis may manifest itself in the future. This psychiatric emergency can cause serious harm to both the mother and the baby, so postpartum psychosis should be recognized and treated as quickly as possible. There is no single guideline for the treatment of postpartum psychosis. Therefore, the treatment must be meticulously chosen by the clinicians according to the clinical characteristics of each patient. According to the data obtained from many clinics in recent years, it has been seen that the most effective treatments are antipsychotics, lithium, mood stabilizers, antidepressants, benzodiazepines, and electroconvulsive therapy (ECT). Therefore, facilitating and accelerating the clinician's choice among these options will significantly contribute to managing postpartum psychosis. This review presents an analysis of current pharmacological treatment modalities in the treatment of postpartum psychosis.

Keywords: Postpartum, Pregnancy, Psychosis.

ÖZET

Doğum sonrası psikoz, duygudurum dalgalanmaları, anormal düşünce veya davranışlar ve konfüzyon ile karakterize, doğum sonrası gelişen ciddi bir ruh sağlığı acili durumudur. Gebelik ve postpartum dönemde annede gelişen hormonal ve psikolojik değişim, stres, sahip olunan bir psikiyatrik rahatsızlık gibi faktörler, genetik yatkınlıkla birlikte doğum sonrası psikozun gelişiminde önemli bir rol oynar. Bu durum en sık bipolar bozukluk tanısı almış veya alacak hastalarda görülmekle beraber, psikoza sahip, şizofreni ya da şizoaffektif bozukluğu olan majör depresyonlu kadınlarda da daha az sıklıkta ortaya çıkabilir. Bir kısım hastada bu durum postpartum dönemde izole kalabilir ve ileride herhangi bir duygudurum bozan veya psikotik rahatsızlıklara ilerlemez ve hastalık başka bir atakla seyretmezken bir grup hastada bu oluşan psikoz kendini ileride de gösterebilir ve şizofreni gibi psikotik rahatsızlıklar dâhil kişinin yaşamını etkileyen bir duruma evrilebilir. Bu psikiyatrik acil durum hem anneye hem de bebeğe ciddi zararlar verebilmektedir, bu nedenle postpartum psikoz, klinisyenler tarafından en hızlı bir şekilde tanınmalı ve tedavisi en kısa sürede uygulanmalıdır. Doğum sonrası psikozun tedavisinde tek bir kılavuz yoktur. Dolayısıyla hastalara uygulanacak tedavinin, klinisyenler tarafından her hastanın klinik özelliklerine göre titizlikle seçilmesi önem arz etmektedir. Son yıllarda birçok kliniklerden elde edilen verilere göre en efektif tedavilerin, antipsikotikler, lityum, duygudurum düzenleyiciler, benzodiyazepinler ve elektrokonvülsif tedavi (EKT) olduğu görülmüştür. Bu nedenle bu seçenekler arasından klinisyenlerin seçim yapmasının kolaylaştırılması ve hızlandırılması, bu denli ciddi bir acil durum olan doğum sonrası psikozun yönetilmesine oldukça katkı sağlayacaktır. Bu derleme, doğum sonrası psikoz tedavisinde güncel farmakolojik tedavi modalitelerinin bir analizini sunmaktadır.

Anahtar Kelimeler: Doğum sonrası, Gebelik, Psikoz.

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How to Cite (APA 7)

Ors, B. (2023). Postpartum Psychosis: A Review of Pharmacological Therapy Options. Health Sciences Student Journal, 3(1), 14-22. https://www.healthssj.com/postpartum-psychosis-a-review-of-pharmacological-therapy-options/

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Şu konuda daha fazla yazı oku: Review Article veya Volume: 3 Number: 1